Critical Analysis: QuidelOrtho (NASDAQ:QDEL) & TNF Pharmaceuticals (NASDAQ:TNFA)

TNF Pharmaceuticals (NASDAQ:TNFA) and QuidelOrtho (NASDAQ:QDEL) are both medical companies, but which is the better business? We will contrast the two companies based on the strength of their institutional ownership, risk, earnings, profitability, dividends, valuation and analyst recommendations.

Profitability

This table compares TNF Pharmaceuticals and QuidelOrtho’s net margins, return on equity and return on assets.

	Net Margins	Return on Equity	Return on Assets
TNF Pharmaceuticals	N/A	-180.71%	-84.27%
QuidelOrtho	-72.84%	3.78%	1.80%

Valuation & Earnings

This table compares TNF Pharmaceuticals and QuidelOrtho”s revenue, earnings per share (EPS) and valuation.

	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
TNF Pharmaceuticals	N/A	N/A	-$4.00 million	N/A	N/A
QuidelOrtho	$2.78 billion	0.93	-$2.03 billion	($30.28)	-1.27

TNF Pharmaceuticals has higher earnings, but lower revenue than QuidelOrtho.

Volatility & Risk

TNF Pharmaceuticals has a beta of 2.13, indicating that its stock price is 113% more volatile than the S&P 500. Comparatively, QuidelOrtho has a beta of 0.08, indicating that its stock price is 92% less volatile than the S&P 500.

Analyst Ratings

This is a summary of current recommendations and price targets for TNF Pharmaceuticals and QuidelOrtho, as provided by MarketBeat.

	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
TNF Pharmaceuticals	0	0	0	0	0.00
QuidelOrtho	0	3	3	0	2.50

QuidelOrtho has a consensus target price of $51.20, suggesting a potential upside of 33.17%. Given QuidelOrtho’s stronger consensus rating and higher possible upside, analysts plainly believe QuidelOrtho is more favorable than TNF Pharmaceuticals.

Institutional & Insider Ownership

9.6% of TNF Pharmaceuticals shares are held by institutional investors. Comparatively, 99.0% of QuidelOrtho shares are held by institutional investors. 1.2% of TNF Pharmaceuticals shares are held by company insiders. Comparatively, 1.0% of QuidelOrtho shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Summary

QuidelOrtho beats TNF Pharmaceuticals on 7 of the 11 factors compared between the two stocks.

About TNF Pharmaceuticals

TNF Pharmaceuticals, Inc. operates as a clinical stage pharmaceutical company. It focuses on developing two novel therapeutic platforms that treat the causes of disease rather than addressing the symptoms. Its MYMD-1 is a drug platform based on a clinical stage small molecule that regulates the immune system to control TNF-a, which drives chronic inflammation, and other pro-inflammatory cell signaling cytokines. The MYMD-1 is being developed to delay aging, increase longevity, and treat autoimmune diseases. The company’s second drug platform, Supera-CBD, is being developed to treat chronic pain, addiction, and epilepsy. The Supera-CBD is a novel synthetic derivative of cannabidiol (CBD) and is being developed to address and improve the growing CBD market, which includes FDA approved drugs and CBD products not regulated as drugs. TNF Pharmaceuticals, Inc. was formerly known as MyMD Pharmaceuticals, Inc. and changed its name to TNF Pharmaceuticals, Inc. in July 2024. The company was founded in 2014 and is headquartered in Baltimore, Maryland.

About QuidelOrtho

QuidelOrtho Corporation provides diagnostic testing solutions. The company operates through Labs, Transfusion Medicine, Point-of-Care, and Molecular Diagnostics business units. The Labs business unit provides clinical chemistry laboratory instruments and tests that measure target chemicals in bodily fluids for the evaluation of health and the clinical management of patients; immunoassay laboratory instruments and tests, which measure proteins as they act as antigens in the spread of disease, antibodies in the immune response spurred by disease, or markers of proper organ function and health; testing products to detect and monitor disease progression across a spectrum of therapeutic areas; and specialized diagnostic solutions. The Transfusion Medicine business unit offers immunohematology instruments and tests used for blood typing to ensure patient-donor compatibility in blood transfusions; and donor screening instruments and tests used for blood and plasma screening for infectious diseases. The Point-of-Care business unit provides instruments and tests to provide rapid results across a continuum of point-of-care settings. The Molecular Diagnostics business unit offers polymerase chain reaction thermocyclers; amplification systems; and sample-to-result molecular instruments and tests for syndromic infectious disease diagnostics. The company sells its products directly to end users through a direct sales force; and through a network of distributors for professional use in physician offices, hospitals, clinical laboratories, reference laboratories, urgent care clinics, universities, retail clinics, pharmacies, wellness screening centers, blood banks, and donor centers, as well as for individual, non-professional, and over-the-counter use. It operates in North America, Europe, the Middle East, Africa, China, and internationally. The company was incorporated in 1979 and is headquartered in San Diego, California.