Aptevo Therapeutics (NASDAQ:APVO) & Aprea Therapeutics (NASDAQ:APRE) Financial Review

Aprea Therapeutics (NASDAQ:APREGet Free Report) and Aptevo Therapeutics (NASDAQ:APVOGet Free Report) are both small-cap medical companies, but which is the superior business? We will contrast the two businesses based on the strength of their risk, valuation, dividends, profitability, institutional ownership, earnings and analyst recommendations.

Analyst Ratings

This is a summary of recent recommendations and price targets for Aprea Therapeutics and Aptevo Therapeutics, as provided by MarketBeat.com.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Aprea Therapeutics 0 0 2 0 3.00
Aptevo Therapeutics 0 0 1 0 3.00

Aprea Therapeutics currently has a consensus price target of $15.50, suggesting a potential upside of 432.65%. Aptevo Therapeutics has a consensus price target of $8.00, suggesting a potential upside of 2,499.94%. Given Aptevo Therapeutics’ higher possible upside, analysts clearly believe Aptevo Therapeutics is more favorable than Aprea Therapeutics.

Volatility and Risk

Aprea Therapeutics has a beta of 0.97, suggesting that its stock price is 3% less volatile than the S&P 500. Comparatively, Aptevo Therapeutics has a beta of 5.07, suggesting that its stock price is 407% more volatile than the S&P 500.

Insider & Institutional Ownership

34.2% of Aprea Therapeutics shares are held by institutional investors. Comparatively, 8.1% of Aptevo Therapeutics shares are held by institutional investors. 12.8% of Aprea Therapeutics shares are held by company insiders. Comparatively, 0.1% of Aptevo Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

Earnings and Valuation

This table compares Aprea Therapeutics and Aptevo Therapeutics”s revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Aprea Therapeutics $580,000.00 27.24 -$14.29 million ($2.81) -1.04
Aptevo Therapeutics $3.11 million 1.83 -$17.41 million N/A N/A

Aprea Therapeutics has higher earnings, but lower revenue than Aptevo Therapeutics.

Profitability

This table compares Aprea Therapeutics and Aptevo Therapeutics’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Aprea Therapeutics -1,029.50% -57.86% -47.94%
Aptevo Therapeutics N/A -353.04% -132.42%

Summary

Aprea Therapeutics beats Aptevo Therapeutics on 7 of the 11 factors compared between the two stocks.

About Aprea Therapeutics

(Get Free Report)

Aprea Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing novel synthetic lethality-based cancer therapeutics that targets DNA damage response pathways. Its lead product candidate is the ATRN-119 that is in Phase I clinical trials for treating advanced solid tumors. The company is also developing ATRN-1051 for the treatment of ovarian cancer; and APRE-DDRi for the treatment of advanced solid tumors. The company is headquartered in Doylestown, Pennsylvania.

About Aptevo Therapeutics

(Get Free Report)

Aptevo Therapeutics Inc., a clinical-stage research and development biotechnology company, focuses on developing immunotherapeutic candidates for the treatment of various forms of cancer in the United States. It develops its products using ADAPTIR and ADAPTIR-FLEX platforms to generate monospecific, bispecific, and multi-specific antibody candidates capable of enhancing the human immune system against cancer cells. The company's lead clinical blood cancer candidate is APVO436 that is in Phase 1b/2 clinical trial for acute myelogenous leukemia. It is also developing ALG.APV-527, a novel investigational bispecific ADAPTIR candidate that is in Phase 1 clinical trial for NSCLC, head and neck, colorectal, pancreatic, breast, and other solid tumors; APVO603, a preclinical dual agonist bispecific ADAPTIR candidate for multiple solid tumors; APVO442, a novel bispecific candidate based on the ADAPTIR-FLEX platform technology for multiple solid tumors; and APVO711, a preclinical dual mechanism bispecific ADAPTIR candidate for prostate cancer. The company has a collaboration and option agreement with Alligator Bioscience AB to develop ALG.APV-527. Aptevo Therapeutics Inc. was incorporated in 2016 and is headquartered in Seattle, Washington.

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